Plant Factory

Phytotron

Growth Chamber

Culture stand & Duct

 

Heat pump chiller

Whale Tron System

Bioassay System

 

CTHU

Clean Room

Animal Room

 

Humidity Equipment

Humidity Chamber

Low Temperature

Remote System

Peripheral Equipment

 
 

 

 

> Products > Animal Room

 

 

 

 

Overview

The experimental animal facility plays an important role in the substitution of clinical trail. Animal room is classified as significance system that conducts on stabilizing experiment.

 
 

Application

  • Inside the building Type
  • Container Type
 
 

Concept of GLP

In accordance with GLP(Good Laboratory Practice), it is necessary to follow the standards when conducting animal experiments. The strict regulations are need for verifying the validity of experiments in the medical substance.

FDA have implemented a law to regulate stability assessment since 1979. In addition, legislation about GLP has been enacted by authorities of Japan in 1983. GLPs standard includes managing animal experiments, regulating a structure of animal room.

 
 

Environmental condition criterion

Animals Category

mouse

Rats

Hamster

Marmot

Rabbit

Monkey

Cat

Dog

Temperature

20 ~ 26

18 ~ 28

Humidity

(To be not less than 30%, 70% or more) from 40 to 60%

Cleanliness

class 10,000 (Barrier zone is not breeding animals)

Cleanliness

Dust

class 10,000 (Barrier zone is not breeding animals)

Drop bacteria

3 Below(Barrier zone is not breeding animals)

30 Below

30 Below (Animal breeding areas not normally)

Smell

Does not exceed the ammonia concentration 20ppm

Flow rate

13~18/sec

Like

5mmH2O increases in static pressure difference. Higher 15mmH2O (SPF barrier zone) at constant pressure difference (isolators)

 

150pa higher than the static pressure difference around the hall (Isolrator)

Ventilation frequency

6 to 15 times / h (depending on the supply and exhaust change method)

Roughness

150 ~ 300 Lux (bottom 40 ~ 85 cm)

Noise

Does not exceed 60 dB (A) to

 

- Class nine minutes of the classification of NASA
-
Kord 9cm diameter opening 30 minutes (blood agar 48 h)

 
 

Ventilation requirement

Category

Temperature()

Humidity()

Weight(g)

Occupied space()

Ventilation(/h)

Mice

18~26

40~60

22

9.62*10-4

0.25

Hamster

18~26

40~70

120

1.87*10-3

0.7

Rabbit

18~21

40~60

~3600

0.116

21

Cat

18~29

30~70

~3700

0.17

21

mouse

18~26

40~70

250

3.34*10-3

1.4

Dog

18~29

30~70

~22,700

1.27

128

Primates

18~29

30~70

~5450

0.283

31

 
 

Temperature & Moisture conditions depending on species

References animal kind 

ASHRAE

Animal
Research Facility

G.L.P

Temperature
( DB)

Humidity
(% RH)

Temperature
( DB)

Humidity
(% RH)

Temperature
( DB)

Humidity
(% RH)

Mouse

18 ~ 26

40 ~ 70

20 ~ 26

40 ~ 60

20 ~ 26

46 ~ 60

Rat

18 ~ 26

40 ~ 70

20 ~ 26

40 ~ 60

20 ~ 26

46 ~ 60

Hamster

18 ~ 26

40 ~ 70

20 ~ 26

40 ~ 60

20 ~ 26

46 ~ 60

Marmot

18 ~ 26

40 ~ 70

20 ~ 26

40 ~ 60

20 ~ 26

46 ~ 60

Rabbit

16 ~ 21

40 ~ 45

18 ~ 28

40 ~ 60

18 ~ 28

46 ~ 60

Cat

18 ~ 29

40 ~ 45

18 ~ 28

40 ~ 60

18 ~ 28

46 ~ 60

Dog

18 ~ 29

40 ~ 55

18 ~ 28

40 ~ 60

18 ~ 28

46 ~ 60

Primates

18 ~ 29

40 ~ 60

18 ~ 28

40 ~ 60

18 ~ 28

46 ~ 60

 

- ASHRAE : Handbook, 1982 Applications , 1982, p.14. 14
- Laboratory Animal Research Facility Based on Laboratory Animal Facilities Construction and Equipment Guide Line, 1983

 
 

Standards for Bio clean room. (NHB-5340-2)

Geupbyeol

Particle

Biological particles

Diameter(um)

Cumulative particle
(Pc / ) 

Part flow (improved / )

Precipitation amount
(dog / )

NASA

209B

NASA

209B

NASA

209B

NASA

209B

100

0.5

0.5

3.5

3.5

0.0035

0.0035

12,900

12,900

10,000

0.5

0.5

350

350

0.0176

0.0176

64,600

64,600

5.0

5.0

2.3

2.3

100,000

0.5

0.5

3,500

3,500

0.0884

0.0884

323,000

323,000

5.0

5.0

25

25

Geupbyeol

Pressure (mmAq)

Temp( )

Humidity( )

Airflow
(
ventilation frequency)

Illuminance (Lux)

100

1.3 or later

Not political

40~45

Laminar way

1,080~1,620

10,000

0.45

±0.1m/s

 

100,000

Turbulence scheme 28 times / hour

 

 
 
 

Functional structure

  • Breeding room : Lighting is controlled automatically depending on day and night
  • Vestibule : establishment of buffer zone
  • Corridor : to facilitate movement / more than 1.3meters are needed
  • Clean preparation room : sterilization room. high pressure steam sterilizers, and Pass box are installed
  • Air shower area : Installed in accordance with regulations such as air attachment, air current, and inter lock etc
  • Sterilization room : Installed with abrasion&chemical resistance materials to reduce contamination
  • Operating room : It is common to install the asepsis operating room
  • Recovery room : accessibility options
 
 

Assembled & container type

 

Features

  • Control temperature and moisture accurately by Hot Gas By Pass
  • 24hours, 24steps, and 24sets are settable
  • Constant wind speed
  • Separated type shelves
  • Classified as significance system that conducts on stabilizing experiment.